--disable-module-relay yields to a Bug:

At a hardened Gentoo Linux the configure option yields to a

# tor --verify-config 
Mar 19 19:44:35.839 [notice] Tor 0.4.3.3-alpha running on Linux with Libevent 2.1.8-stable, OpenSSL LibreSSL 3.0.2, Zlib 1.2.11, Liblzma 5.2.4, and Libzstd N/A.
Mar 19 19:44:35.840 [notice] Tor can't help you if you use it wrong! Learn how to be safe at https://www.torproject.org/download/download#warning
Mar 19 19:44:35.840 [notice] This version is not a stable Tor release. Expect more bugs than usual.
Mar 19 19:44:35.840 [notice] Read configuration file "/etc/tor/torrc".
Mar 19 19:44:35.843 [err] tor_assertion_failed_(): Bug: src/app/config/config.c:1473: options_switch_id: Assertion have_low_ports != -1 failed; aborting. (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.844 [err] Bug: Tor 0.4.3.3-alpha: Assertion have_low_ports != -1 failed in options_switch_id at src/app/config/config.c:1473: . Stack trace: (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(log_backtrace_impl+0x59) [0x5564677d3ab9] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(tor_assertion_failed_+0x150) [0x5564677cecb0] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(set_options+0x404) [0x5564677535d4] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(+0x1648a0) [0x5564677548a0] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(options_init_from_string+0x119) [0x556467754af9] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(options_init_from_torrc+0x359) [0x5564677550f9] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.845 [err] Bug:     tor(tor_init+0x1c7) [0x55646764ade7] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.846 [err] Bug:     tor(tor_run_main+0x71) [0x55646764b4e1] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.846 [err] Bug:     tor(tor_main+0x46) [0x55646764a006] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.846 [err] Bug:     tor(main+0x19) [0x556467649bd9] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.846 [err] Bug:     /lib64/libc.so.6(__libc_start_main+0xeb) [0x7ff9817b8f1b] (on Tor 0.4.3.3-alpha )
Mar 19 19:44:35.846 [err] Bug:     tor(_start+0x2a) [0x556467649c2a] (on Tor 0.4.3.3-alpha )
Aborted

The same tarball at the same system works fine with that option being enabled. The config is

cat /etc/tor/torrc
User tor
PIDFile /var/run/tor/tor.pid
Log notice file /tmp/notice.log
DataDirectory /var/lib/tor/data

CookieAuthentication 1
ControlPort 9051

SocksPort 9050

SandBox 1